CD20 Antibody

• Catalog Number: orb1821649
• Category: Antibodies
• Description: CD20 Antibody
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: B9E9
• Tested applications: WB
• Reactivity: Human
• Isotype: IgG
• Immunogen: This antibody was raised against human CD20.
• Concentration: 1 mg/ml
• Conjugation: Unconjugated
• Target: CD20
• UniProt ID: P11836
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: MS4A1; B-lymphocyte antigen CD20;MS4A1; B-lymphocy
• Note: For research use only
• Application notes: This antibody has been used in western blot detection of CD20 in human plasma, revealing elevated CD20 levels in plasma from chronic lymphocytic leukemia patients (Manshouri et al, 2003). An scFv derived from this antibody fused to streptavidin has been investigated as a method of pretargeted radioimmunotherapy for lymphomas (Schultz et al, 2000), and has been demonstrated to be non-toxic in a phase I trial of non-Hodgkin lymphoma patients (Forero et al, 2004). Additionally, measles viruses engineered to express this scFv are able to enter CD20+ target cells through interaction with CD20 antigen, with clinical relevance for lymphoma therapy (Bucheit et al, 2003).
• Expiration Date: 12 months from date of receipt.