YBX1 antibody

• Catalog Number: orb107089
• Category: Antibodies
• Description: Rabbot polyclonal to YBX1. Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Clone Number: RB41913
• Tested applications: IF, WB
• Predicted Reactivity: Mouse, Rabbit, Rat
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Dilution range: WB: 1:1000, IF/ICC: 1:10-50
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• MW: 35924
• Target: YBX1
• UniProt ID: P67809
• NCBI: NP_004550.2
• Alternative names: Nuclease-sensitive element-binding protein 1, CCAA
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Confocal immunofluoroscence analysis of A549 cell using YBX1 antibody (Center)