TARP Gamma2/4/8 (Stargazin) antibody

• Catalog Number: orb150192
• Category: Antibodies
• Description: Mouse monoclonal to TARP Gamma2 (ATTO-488). Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state. There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T). Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival..
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: S245-36
• Tested applications: ICC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG2A
• Immunogen: Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000), ICC/IF (1:100)
• Conjugation: ATTO-488
• MW: 35-55kDa
• Target: Stargazin
• Entrez: 84347
• UniProt ID: Q71RJ2
• NCBI: NP_445803.1
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Alternative names: CACNG2 antibody, Calcium channel voltage dependent
• Note: For research use only
• Application notes: 1 µg/ml of SMC-422 was sufficient for detection of TARP Gamma2/4/8 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.