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Catalog Number | orb1732753 |
---|---|
Category | Antibodies |
Description | As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 3E7 |
Tested applications | ICC, IP, WB |
Reactivity | Human |
Isotype | Mouse IgG2b |
Immunogen | Purified recombinant human RPA32/RPA2 protein fragments expressed in E.coli. |
Concentration | 1mg/ml |
Dilution range | IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200 |
Conjugation | Unconjugated |
MW | Calculated MW: 29 kDa; Observed MW: 32 kDa |
Entrez | 6118 |
UniProt ID | P15927 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3. |
Alternative names | 60S acidic ribosomal protein P1; AA409079; AI32519 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
FC, ICC, IF, IHC, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
ELISA, IF, IHC, IP, WB | |
Human | |
Rabbit | |
Polyclonal | |
Unconjugated |
ICC, IHC-P, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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