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RNF43 Protein, Human, Recombinant (His)

RNF43 Protein, Human, Recombinant (His)

Catalog Number: orb1955573

DispatchUsually dispatched within 5-10 working days
$ 440.00
Catalog Numberorb1955573
CategoryProteins
DescriptionRNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expressed oncogenes in malignant colorectal tumors. RNF43 is a tumour suppressor gene that suppresses the Wnt-beta-catenin signalling pathway. RNF43 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q68DV7-1.
TagC-His
Purity98.70%
MW20.5 kDa (predicted); 27 and 23.8 kDa (reducing conditions)
UniProt IDQ68DV7
Expression SystemHEK293 Cells
Biological OriginHuman
Biological ActivityRNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expressed oncogenes in malignant colorectal tumors. RNF43 is a tumour suppressor gene that suppresses the Wnt-beta-catenin signalling pathway. RNF43 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q68DV7-1.
Expression RegionA DNA sequence encoding the human RNF43 (NP_060233.3) (Met1-Tyr197) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Gly 24
Storage-20°C
NoteFor research use only
Application notesA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Expiration Date6 months from date of receipt.