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Recombinant Human FGF9
Catalog Number: orb1921835
| Catalog Number | orb1921835 |
|---|---|
| Category | Proteins |
| Description | Fibrolast growth factor 9 (FGF9) is an FGF9 subfamily (including FGF9, 16, and 20) member. Unlike other secreted proteins which have a cleavable N-terminal secreted signal peptide, FGF9/16/20 have non-cleaved N-terminal signal peptides. As intercellular signaling molecules, they are involved in a variety of complex responses in animal development. Cardiogenesis is controlled by many members of the transcription factor family. Evidence suggests that FGF signaling, including the FGF9 subfamily, has a pretty close association with these cardiac-specific genes. In addition, recent studies have shown that the FGF9 subfamily maintains functional adaptation and survival after myocardial infarction in adult myocardium. Since FGF9/16/20 are secreted proteins, their function characterization in cardiac regeneration can promote their potential to be developed for the treatment of cardioprotection and revascularization. In the postmyocardial infarction heart, FGF9 promotes cardiomyocyte hypertrophy by activating BMP6 and its downstream targets. FGF9 also activates c-Kit stem cells and enhances angiogenesis in the infracted diabetic heart. In addition, studies have shown that FGF-9 signaling can stimulate mesenchymal cell proliferation and migration of mesonephric cells into the testis during development, contributing to the formation of the interstitial compartment of the testis. |
| Form/Appearance | Lyophilized Powder |
| Purity | ≥95% |
| UniProt ID | P31371 |
| MW | 23.2kDa |
| Application notes | Application Notes: For research use only. Minimum Sample Size: 50μg/vial |
| Expression System | Eukaryotic cell |
| Endotoxins | ≤10 EU/mg |
| Source | CHO Cell |
| Biological Origin | Human |
| Storage | Use a manual defrost freezer and avoid repeated freeze - thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -88°C under sterile conditions after reconstitution. |
| Alternative names | Fibroblast Growth Factor 9, Heparin-Binding Growth Read more... |
| Note | For research use only |
| Entrez | 2254 |
- Item 1 of 1
Human FGF9 protein (Active) [orb359154]
> 95% as determined by SDS-PAGE and HPLC.
23.3 kDa
E.Coli
5 μg, 100 μg, 500 μg - Item 1 of 1
Human FGF9 protein [orb594735]
Greater than 95% as determined by SDS-PAGE.
23.44 kDa
E.coli
1 mg, 500 μg, 10 μg, 50 μg - Item 1 of 1
Human FGF-9 Protein [orb1471703]
Greater than 95% as determined by reducing SDS-PAGE.
23.44 KDa
Mammalian
50 μg, 10 μg Human FGF9 protein [orb391739]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
E. coli
500 μg, 50 μg, 10 μgRecombinant Human Fibroblast growth factor 9 (FGF9), partial (Active) [orb2657900]
Greater than 95% as determined by SDS-PAGE.
23.2 kDa
Mammalian cell
10 μg, 1 mg, 50 μg
