Rat IL-7 protein

• Catalog Number: orb107751
• Category: Proteins
• Description: Interleukin-7 (IL-7) is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus. It binds to the IL-7receptor, a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation ofhematopoietic stem cells into lymphoid progenitor cells and also stimulates proliferation of B cells, T cells and NK cells.Furthermore, IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies andduring HIV infection. Rat IL-7 contains 129 amino acid residues and has three disulfide bonds. In addition, it has approximately57 % and 88 % amino acid sequence identity with human and murine IL-7.
• Tested applications: HPLC, SDS-PAGE
• Purity: > 95 % by SDS-PAGE and HPLC analyses
• Conjugation: Unconjugated
• MW: 14. 9 kDa
• Target: IL-7
• Protein Sequence: DCHIKDKDGK AFGSVLMISI NQLDKMTGTD SDCPNNEPNF FKKHLCDDTKEAAFLNRAAR KLRQFLKMNI SEEFNDHLLR VSDGTQTLVN CTSKEEKTIKEQKKNDPCFL KRLLREIKTC WNKILKGSI
• Biological Origin: E.coli
• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 m filtered concentrated solution in PBS, pH 7.4.
• Alternative names: Rat Interleukin-7 protein
• Note: For research use only
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Rat IL-7 protein