PIAS1 antibody

• Catalog Number: orb66685
• Category: Antibodies
• Description: Mouse monoclonal to PIAS1.PIAS1 is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator oftranscription)] family of transcriptional modulators. PIAS1 functions as an E3 small ubiquitin-likemodifier (SUMO) ligase. It stabilizes the interaction between UBE2I and the substrate, and functionsas a SUMO-tethering factor. PIAS1 plays an important role in the transcriptional regulation ofnumerous cellular pathways, including STAT, NFkB, p53 and the steroid hormone signalingpathways. Recent studies revealed that PIAS1 is an important regulator for innate immunity,inflammatory cytokine signaling and regulatory T cell differentiation.
• Species/Host: Mouse
• Clonality: Monoclonal
• Tested applications: WB
• Reactivity: Mouse
• Immunogen: C-terminal region of mouse PIAS1
• Dilution range: WB:1:1000-1:5000
• Purity: Caprylic Acid-Ammonium Sulfate precipitation
• Conjugation: Unconjugated
• MW: 72
• UniProt ID: P49763
• Storage: -20°C
• Buffer/Preservatives: 0.02% Thimerosal
• Alternative names: anti-PIAS1 antibody,anti-Protein inhibitor of acti
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from mouse thymus using PIAS1 antibody