NQO1 Antibody

• Catalog Number: orb2637469
• Category: Antibodies
• Description: NAD(P)H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC (non-small cell lung cancer), suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
• Antibody Type: Primary Antibody
• Dilution range: Western blot: 1-3ug/ml
• Purity: Protein A affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This NQO1 antibody is available for research use only.
• Entrez: 1728
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 1X PBS, pH 7.4
• Note: For research use only
• Application notes: Provided assay concentrations are suggestions only, NQO1 antibody titration may be required for optimal results.
• Expiration Date: 12 months from date of receipt.

Western blot testing of human samples using NQO1 antibody at 1 ug/ml. Predicted molecular weight ~30kDa.