MLKL Antibody

• Catalog Number: orb1732945
• Category: Antibodies
• Description: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 6A2
• Tested applications: IHC
• Reactivity: Human
• Isotype: Mouse IgG1
• Immunogen: Synthetic peptide conjugated to KLH.
• Concentration: 1mg/ml
• Dilution range: IHC: 1/50-1/100
• Conjugation: Unconjugated
• Entrez: 197259
• UniProt ID: Q8NB16
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: MLKL
• Note: For research use only
• Expiration Date: 12 months from date of receipt.