LK-2

• Catalog Number: orb2664395
• Category: Small Molecules
• Description: LK-2 functions as an antagonist to ASIC1a with a dissociation constant (Kd) of 1.9 µM. It effectively reduces the glutamate-induced enhancement of ASIC1a currents, exhibiting an IC50 value of 6.6 µM. In ischemic stroke models in mice, LK-2 demonstrates neuroprotective properties, enhancing motor and coordination abilities. Additionally, LK-2 is permeable to the blood-brain barrier (BBB).
• CAS Number: 2649762-09-2
• Purity: 98.00%
• MW: 300.25
• SMILES: O=C(O)C1NCCN(C1)C(C=2C=CC=CC2)P(=O)(O)O
• Formula: C₁₂H₁₇N₂O₅P
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.