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Catalog Number | orb107749 |
---|---|
Category | Proteins |
Description | Recombinant Rat Interleukin-5. IL-5, also named B-cell differentiation factor I, eosinophil differentiation factor and TRF, is belonging to the cytokine family and the IL-5 gene is in close proximity to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in TH2 cells. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunroglobulin secretion. It is also a key mediator in eosinophil activation. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma.Rat IL-5 is a 132-amino acid (115 in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely IL-3 and GM-CSF), this glycoprotein in its active form is a homodimer. |
Tested applications | HPLC, SDS-PAGE |
Conjugation | Unconjugated |
Target | IL-5 |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of IL-5 protein
Unconjugated | |
85% | |
37.7 kDa | |
Human IL-5 R alpha, His Tag (orb257612) is expressed from human 293 cells (HEK293). It contains AA Asp 21 - Glu 335 (Accession # NP_000555). |
Greater than 95% as determined by SDS-PAGE. | |
14.2 kDa | |
Mammalian cell |
> 98% as determined by SDS-PAGE and HPLC. | |
13.1 kDa | |
E.Coli |
> 98% as determined by SDS-PAGE and HPLC. | |
13.3 kDa | |
E.Coli |
> 98% as determined by SDS-PAGE and HPLC. | |
13.1 kDa | |
E.Coli |
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