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Catalog Number | orb1960143 |
---|---|
Category | Small Molecules |
Description | IgG1 Fc Protein, Mouse, Recombinant |
Purity | 98.00% |
MW | The protein has a predicted MW of 25.7 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result. |
Biological Activity | Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Unconjugated | |
95% | |
24.3 kDa | |
Mouse IgG Fc, Tag Free (orb257565) is expressed from human 293 cells (HEK293). It contains AA Val 111 - Lys 324 (Accession # AAK53870.1). |
> 95% by Tris-Bis PAGE, > 95% by SEC-HPLC | |
KMP2022, Recombinant Mouse IgG1 Fc Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Val98-Lys324) of Mouse IgG1 Fc fused with no tag . |
Unconjugated | |
90% | |
111.2 kDa | |
Human Cadherin-17 Protein, Mouse IgG1 Fc Tag (orb1675334) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1). |
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