Mouse Fc Protein

• Catalog Number: orb257565
• Category: Proteins
• Description: Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
• Reactivity: Mouse
• Tag: Native
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 24.3 kDa
• Target: IgG1 Fc
• Protein Sequence: AAK53870.1
• Source: Mouse IgG Fc, Tag Free (orb257565) is expressed from human 293 cells (HEK293). It contains AA Val 111 - Lys 324 (Accession # AAK53870.1).
• Expression System: HEK293
• Expression Region: Val 111 - Lys 324
• Endotoxins: 1.0 EU per μg
• NCBI: AAK53870.1
• Storage: -20℃
• Buffer/Preservatives: 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Alternative names: IgG1
• Note: For research use only
• Application notes: This protein carries no "tag". The protein has a calculated MW of 24.3 kDa. The protein migrates as 28-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Mouse IgG Fc protein

Mouse IgG Fc protein

Mouse IgG Fc protein