Human Cadherin-17 / CDH17 Protein, Mouse IgG1 Fc Tag

• Catalog Number: orb1675334
• Category: Proteins
• Description: Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
• Reactivity: Human
• Tag: C-mFc(mIgG1)
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 111.2 kDa
• Target: Cadherin-17
• Protein Sequence: Gln 23 - Met 787
• Source: Human Cadherin-17 Protein, Mouse IgG1 Fc Tag (orb1675334) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1).
• Expression System: HEK293
• Expression Region: Gln 23 - Met 787
• Endotoxins: 1.0 EU per μg
• Storage: -20℃
• Buffer/Preservatives: 20 mM Tris, 150 mM NaCl, pH8.0
• Note: For research use only
• Application notes: This protein carries a mouse IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 111.2 kDa. The protein migrates as 130-135 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.