Granzyme B Antibody

• Catalog Number: orb1729758
• Category: Antibodies
• Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: Synthesized peptide derived from human Granzyme B Polyclonal
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100; ELISA: 1/10000
• Conjugation: Unconjugated
• MW: Calculated MW: 28 kDa; Observed MW: 40 kDa
• Entrez: 3002
• UniProt ID: P10144
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: Granzyme B; Cathepsin G-like 1; CTSGL1; Lymphocyte
• Note: For research use only
• Expiration Date: 12 months from date of receipt.