EGR2 antibody

• Catalog Number: orb131906
• Category: Antibodies
• Description: Rabbit polyclonal to EGR2. E3 SUMO-protein ligase EGR2 belongs to the EGR C2H2-type zinc-finger protein family. EGR2 is a sequence-specific DNA-binding transcription factor and binds to two specific DNA sites located in the promoter region of HOXA4. EGR2 helps SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in EGR2 are a cause of congenital hypomyelination neuropathy (CHN), of Charcot-Marie-Tooth disease type 1D (CMT1D), and of Dejerine-Sottas syndrome (DSS).
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ChIP, IP, WB
• Reactivity: Human, Mouse
• Immunogen: C-terminal region of human EGR2
• Concentration: 100 μg/ml BSA
• Dilution range: WB:1:1000-1:3000,IF/ICC:1:100-1:200
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 50
• UniProt ID: P11161
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti E3 SUMO-protein ligase EGR2 antibody, anti AT
• Note: For research use only
• Application notes: WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human EGR2.
• Expiration Date: 12 months from date of receipt.