COL4A1 Antibody

• Catalog Number: orb1730555
• Category: Antibodies
• Description: <span style="font-family:"font-size:14px;background-color:#FFFFFF;">This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: Synthesized peptide derived from COL4A1. at AA range: 1428-1443
• Dilution range: WB: 1/500-1/2000; ELISA: 1/10000-1/20000
• Conjugation: Unconjugated
• MW: 161kDa
• Entrez: 1282
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3
• Alternative names: BS BSVD1, COL4A1s, PADMAL, RATOR
• Note: For research use only
• Expiration Date: 12 months from date of receipt.