Chk2 Antibody

• Catalog Number: orb1732144
• Category: Antibodies
• Description: These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, IP, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Recombinant protein of human Chk2
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 61 kDa; Observed MW: 61 kDa
• Entrez: 11200
• UniProt ID: O96017
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein
• Note: For research use only
• Expiration Date: 12 months from date of receipt.