CDH1 antibody

• Catalog Number: orb66765
• Category: Antibodies
• Description: Rabbit polyclonal to CDH1.Cadherin-1 (CDH1) is a single-pass membrane protein. Cadherins are calcium-dependent celladhesion proteins. They preferentially interact with themselves in a homophilic manner in connectingcells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved inmechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. It has a potentinvasive suppressor role. It is a ligand for integrin alpha-E/beta-7. Defects in CDH1 are the cause ofhereditary diffuse gastric cancer (HDGC) and are a cause of susceptibility to endometrial cancer(ENDMC) and ovarian cancer (OC).
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: C-terminal region of human CDH1
• Dilution range: WB:1:500-1:1000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 97
• UniProt ID: P12830
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-CDH1 antibody,anti-Cadherin1 antibody,anti-CA
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human MCF7(Lane1) and human Hela(Lane2) using CDH1 antibody