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Calbindin Antibody / CALB1

Catalog Number: orb640001

DispatchUsually dispatched within 5-10 working days
$ 410.00
Catalog Numberorb640001
CategoryAntibodies
DescriptionThe family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.
Species/HostMouse
ClonalityMonoclonal
Clone NumberCALB1/2364
Tested applicationsELISA
ReactivityHuman
IsotypeMouse IgG1, kappa
ImmunogenA recombinant human partial protein (amino acids 7-96) was used as the immunogen for this Calbindin 1 antibody.
Antibody TypePrimary Antibody
Dilution rangeELISA (order BSA-free format for coating)
PurityProtein G affinity chromatography
ConjugationUnconjugated
Formula0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Hazard InformationThis Calbindin 1 antibody is available for research use only.
UniProt IDP05937
StorageStore the Calbindin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Buffer/Preservatives0.2 mg/ml with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
NoteFor research use only
Application notesOptimal dilution of the antibody should be determined by the researcher.
Expiration Date12 months from date of receipt.
Calbindin Antibody / CALB1

Analysis of HuProt (TM) microarray containing more than 19000 full-length human proteins using Calbindin 1 antibody (clone CALB1/2364). These results demonstrate the foremost specificity of the CALB1/2364 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

Calbindin Antibody / CALB1

SDS-PAGE analysis of purified, BSA-free Calbindin 1 antibody as confirmation of integrity and purity.

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