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ATG3 Protein, Human, Recombinant
Catalog Number: orb1960986
| Catalog Number | orb1960986 |
|---|---|
| Category | Proteins |
| Description | Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy. |
| Tag | C-6xHis, N-T7 |
| Purity | 98.00% |
| Protein Sequence | Met1-Met314 |
| UniProt ID | Q9NT62 |
| MW | 38 KDa (reducing condition) |
| Application notes | 0 |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy. |
| Expression Region | Met1-Met314 |
| Storage | -20°C |
| Note | For research use only |
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Human ATG3 protein [orb246299]
Greater than 90% as determined by SDS-PAGE.
51.9 kDa
E.coli
20 μg, 100 μg, 1 mg Human ATG3 protein [orb391267]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by reducing SDS-PAGE.
E. coli
500 μg, 50 μg, 10 μgRecombinant Human ATG3 Protein, N-His [orb2834791]
> 90% as determined by SDS-PAGE.
38.17 kDa
100 μg, 50 μg, 20 μgHuman ATG3 protein [orb756180]
ELISA, WB
Greater than 95% as determined by SDS-PAGE
31.5 kDa
E.Coli
1 mg, 100 μg, 50 μg, 200 μgRecombinant Human ATG3 [orb1098691]
ELISA, WB
Greater than 90% by SDS-PAGE gel analyses
56.5 kDa
E.Coli
1 mg, 200 μg, 100 μg, 50 μg
