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Anti-Hu CD270 Purified
Catalog Number: orb1088492
| Catalog Number | orb1088492 |
|---|---|
| Category | Antibodies |
| Description | CD270 is a type I transmembrane protein of the TNFR superfamily, which is expressed on resting T cells, monocytes, and immature dendritic cells. Its ligands, CD258 and CD272, differ in effect on CD270 signaling. Whereas binding to CD258 provides a costimulatory signal, binding to CD272 gives to the cell an inhibitory signal. CD270 also is recognized by herpes simplex glycoprotein D. CD258-CD270 interaction and signaling is implicated in macrophage-derived foam cell-mediated development of atherosclerotic lesions. |
| Clonality | Monoclonal |
| Clone Number | CW10 |
| Tested applications | ELISA, FC, ICC, IP, WB |
| Reactivity | Human |
| Isotype | Mouse IgG1 kappa |
| Immunogen | recombinant human CD270 |
| Antibody Type | Primary Antibody |
| Concentration | 1 mg/ml |
| Purity | Purified by protein-A affinity chromatography. |
| Conjugation | Unconjugated |
| Target | CD270 |
| Entrez | 8764 |
| UniProt ID | Q92956 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Buffer/Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Alternative names | Anti-TNFRSF14 antibody, anti-TR2 antibody, anti-AT Read more... |
| Note | For research use only |
| Application notes | Flow cytometry: Recommended dilution: 1-5 μg/ml. |
| Expiration Date | 12 months from date of receipt. |
Separation of HDLM-2 cells stained using anti-CD270 (CW10) purified antibody (concentration in sample 1.6 μg/ml, GAM APC, red-filled) from HDLM-2 cells unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
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