Amyloid Beta Antibody

• Catalog Number: orb1821629
• Category: Antibodies
• Description: Amyloid Beta Antibody
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 21F12
• Tested applications: ELISA, IHC, IP, WB
• Reactivity: Human
• Isotype: IgG1
• Immunogen: The original antibody was generated by immunizing A/J mice with a synthetic peptide (NH2-CYS-NH-CH2-(CH2)5-CO-GLMVGGVVIA-COOH) as an immunogen.
• Concentration: 1 mg/ml
• Conjugation: Unconjugated
• Target: Amyloid Beta
• UniProt ID: P05067
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Abeta; A-beta; Aβ; Aβ42; Alzheimer disease amyloid
• Note: For research use only
• Application notes: This antibody has very high specificity for Aβ1–42 over Aβ1–40. This antibody is capable of immunoprecipitating Aβ peptides ending at aa position 42 and also p3 peptides (PMID: 8917563). This antibody is also recomended for detection of amyloid beta using sandwich ELISA (PMID: 9037091, 19204155). This antibody was also used in the quantification of the proportion of full-length Aβ using western blotting (PMID: 12787077). This antibody has also been used for the identification of Aβ42 plaques on paraffin frontal sections(PMID: 15215183, 19660650). This antibody is unable to bind plaques in unfixed brain sections. This antibody is also not capable of clearing plaque after in vivo administration (PMID: 10932230).
• Expiration Date: 12 months from date of receipt.