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Catalog Number | orb1954865 |
---|---|
Category | Small Molecules |
Description | Zika virus (ZIKV) (strain Zika SPH2016) ZIKV-E (Stem/anchor domain of flavivirus envelope glycoprotein E) protein (Fc) |
Purity | 98.00% |
MW | Approxiamtely 36.7 kDa |
Biological Activity | Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent with those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross-reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross-reactivity with dengue and YF.Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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