Zika virus (strain Zika SPH2015) E/Envelope protein (His & MBP)

• Catalog Number: orb1954537
• Category: Small Molecules
• Description: Zika virus (strain Zika SPH2015) E/Envelope protein (His & MBP)
• Purity: 98.00%
• MW: Approxiamtely 57.2 kDa
• Biological Activity: Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent with those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross-reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross-reactivity with dengue and YF.Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.