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Catalog Number | orb67087 |
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Category | Antibodies |
Description | Rabbit polyclonal to YAP1.YAP1 is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes protooncogeneproduct. YAP1 contains a WW domain that is found in various structural, regulatory andsignaling molecules in yeast, nematode, and mammals, which be involved in protein-proteininteraction. YAP1 is a transcriptional regulator that can act both as a coactivator and a corepressor.YAP1 is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotalrole in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | N-terminal region of human YAP1 |
Dilution range | WB:1:1000-1:5000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 54 |
UniProt ID | P46937 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-YAP1 antibody,anti-Yorkie homolog antibody,an Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela using YAP1 antibody
ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Polyclonal | |
Unconjugated |
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