WZ3146

• Catalog Number: orb573095
• Category: Small Molecules
• Description: WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).
• CAS Number: [1214265-56-1]
• MW: 464.95
• SMILES: CN1CCN(C2=CC=C(C=C2)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl)CC1
• Formula: C₂₄H₂₅ClN₆O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.