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Catalog Number | orb2647069 |
---|---|
Category | Small Molecules |
Description | Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor with IC50 of 95/160/67/733/78/432 nM for HDAC1/2/3/8/10/11, respectively; shows no activity against Class IIa HDAC4/4/7/9 and HDAC6; demonstrates significant and broad spectrum in vitro and in vivo antitumor activity, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells. |
CAS Number | [1616493-44-7] |
MW | 390.410268068314 |
SMILES | FC1C=CC(=C(C=1)N)NC(C1C=CC(=CC=1)CNC(/C=C/C1C=NC=CC=1)=O)=O |
Formula | C22H19FN4O2 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.76% | |
1616493-44-7 | |
390.41 | |
C22H19FN4O2 |