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Catalog Number | orb1962003 |
---|---|
Category | Small Molecules |
Description | TPO Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 70-90 KDa, reducing conditions |
Biological Activity | Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human Tpo(Met1-Arg846) was fused with the C-terminal His Tag and expressed in Baculovirus-Insect cells. |
≥90% as determined by SDS-PAGE | |
This protein contains the human TPO(Ser22-Gly353) was fused with the N and C-terminal His Tag and expressed in Mammalian cells. |
> 90% as determined by SDS-PAGE | |
27.4 kDa |
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