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Toxin B Protein, Vibriocholerae, Recombinant
Catalog Number: orb1961557
| Catalog Number | orb1961557 |
|---|---|
| Category | Proteins |
| Description | Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself. |
| Tag | Tag Free |
| Purity | 98.00% |
| Protein Sequence | Thr22-Asn124 |
| UniProt ID | P01556 |
| MW | 11 KDa (reducing condition) |
| Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Expression System | E. coli |
| Biological Origin | Vibrio cholerae |
| Biological Activity | Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself. |
| Expression Region | Thr22-Asn124 |
| Storage | -20°C |
| Note | For research use only |
