TLS/FUS Rabbit Polyclonal Antibody

SKU: orb100082

Description

TLS/FUS Rabbit Polyclonal Antibody

Research Area

Cancer Research, DNA and RNA Research, Proto-oncogenes, Signal Transduction, Transcription Factors

Images & Validation

• Tested Applications: WB
• Dilution range: WB=1:500-2000
• Reactivity: Human
• Predicted Reactivity: Bovine, Canine, Equine, Mouse, Porcine, Rabbit, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human TLS (421-526/526aa)
• Target: FUS
• Molecular Weight: 53 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Disclaimer: For research use only

Alternative Names

75 kDa DNA pairing protein; 75 kDa DNA-pairing protein; ALS6; Amyotrophic lateral sclerosis 6; FUS; FUS CHOP; Fus like protein; FUS-CHOP; FUS_HUMAN; FUS1; Fused in sarcoma; Fusion(involved in t(12; 16) in malignant liposarcoma); Fusion derived from t(12; 16) malignant liposarcoma; Fusion gene in myxoid liposarcoma; Heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; hnRNPP2; Oncogene FUS; Oncogene TLS; POMp75; RNA binding protein FUS; RNA-binding protein FUS; TLS; TLS CHOP; TLS-CHOP; Translocated in liposarcoma; Translocated in liposarcoma protein.

Sample: Lane 1: Human 293T cell lysates, Lane 2: Human HeLa cell lysates, Primary: Anti-TLS/FUS (orb100082) at 1/1000 dilution, Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution, Predicted band size: 53 kDa, Observed band size: 65 kDa.

Quick Database Links

Gene Symbol

FUS

UniProt

P35637

References

Abad-Morales, V������ctor et al. mRNA expression analysis of the SUMO pathway genes in the adult mouse retina Biol Open, 4, 224-232 (2015)

PubMed: 25617419

Applications

WB

Reactivity

Mouse