TLR9 antibody

• Catalog Number: orb131753
• Category: Antibodies
• Description: Rabbit polyclonal to TLR9. Toll-like receptor 9 (TLR9) is a single-pass type I membrane protein belonging to the Toll-like receptor family. TLR9 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidinephosphate-guanosine (CpG) dinucleotides. TLR9 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Furthermore, TLR9 controls lymphocyte response to Helicobacter infection.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: C-terminal region of human TLR9
• Concentration: 100 μg/ml BSA
• Dilution range: WB:1:1000-1:3000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 116
• UniProt ID: Q9NR96
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti Toll-like receptor 9 antibody, anti CD289 ant
• Note: For research use only
• Application notes: WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human TLR9.
• Expiration Date: 12 months from date of receipt.