Tetrachlorohydroquinone

• Catalog Number: orb1985049
• Category: Small Molecules
• Description: Tetrachlorohydroquinone (TCHQ), a metabolite of the organochlorine biocide pentachlorophenol, is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of mitochondrial membrane potential and necrosis in splenocytes.
• Purity: 98.00%
• MW: 247.89
• Biological Activity: Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes.
• CAS Number: 87-87-6
• Formula: C₆H₂Cl₄O₂
• SMILES: Oc1c(Cl)c(Cl)c(O)c(Cl)c1Cl
• Storage: -20°C
• Note: For research use only