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Catalog Number | orb2703819 |
---|---|
Category | Antibodies |
Description | Teprotumumab is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research. |
Target | Teprotumumab Biosimilar(Anti-IGF1R / CD221 Reference Antibody) |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Antibody Type | Biosimilar Antibody |
CAS Number | [1036734-93-6] |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Note | For research use only |