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Syntenin Protein, Human, Recombinant (His)

Syntenin Protein, Human, Recombinant (His)

Catalog Number: orb1954944

DispatchUsually dispatched within 5-10 working days
$ 800.00
Catalog Numberorb1954944
CategoryProteins
DescriptionSyntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy.
TagN-His
Purity98.00%
MW34.7 kDa (predicted)
UniProt IDO00560
Expression SystemE. coli
Biological OriginHuman
Biological ActivitySyntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy.
Expression RegionA DNA sequence encoding the human SDCBP (NP_001007068.1) (Met1-Val298) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
Storage-20°C
NoteFor research use only
Application notesA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Expiration Date6 months from date of receipt.
  • Recombinant Human SDCBP/Syntenin-1 Protein, His Tag [orb1551707]

    ≥90% as determined by SDS-PAGE

    This protein contains the human Sdcbp(Ser2-Val298) was fused with the C-terminal His Tag and expressed in E. coli.

    100 μg, 50 μg