Syntenin Protein, Human, Recombinant (His)

Catalog Number: orb1954944

Catalog Number	orb1954944
Category	Proteins
Description	Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy.
Tag	N-His
Purity	98.00%
UniProt ID	O00560
MW	34.7 kDa (predicted)
Application notes	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Expression System	E. coli
Biological Origin	Human
Biological Activity	Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy.
Expression Region	A DNA sequence encoding the human SDCBP (NP_001007068.1) (Met1-Val298) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
Storage	-20°C
Note	For research use only

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human Sdcbp(Ser2-Val298) was fused with the C-terminal His Tag and expressed in E. coli.

Purity:	> 90% as determined by SDS-PAGE.
MW:	33.9 kDa

Purity:	> 90% as determined by SDS-PAGE.
MW:	34.62 kDa