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Catalog Number | orb106948 |
---|---|
Category | Antibodies |
Description | Rabbit polyclonal to SUZ12. Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Clone Number | RB42757 |
Tested applications | WB |
Reactivity | Human, Mouse |
Isotype | Rabbit IgG |
Immunogen | Synthetic Peptide |
Dilution range | WB: 1:1000 |
Form/Appearance | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Conjugation | Unconjugated |
MW | 83055 |
Target | SUZ12 |
UniProt ID | Q15022 |
NCBI | NP_056170.2 |
Alternative names | anti SUZ12 antibody, anti CHET9 antibody, anti JJA Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ICC, IF, IP, WB | |
Human, Mouse, Rat | |
Polyclonal | |
Unconjugated |
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