Stat3 Antibody (C-term Tyr705)

SKU: orb106926

Description

Rabbit polyclonal to Stat3. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

Research Area

Cancer Biology, Cardiovascular Research, Immunology & Inflammation, Infectious Disease & Virology, Microbiology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

• Tested Applications: WB
• Dilution range: WB: 1:1000
• Reactivity: Human
• Predicted Reactivity: Mouse, Porcine, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB42111
• Immunogen: Synthetic Peptide
• Target: STAT3
• Molecular Weight: 88068
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Disclaimer: For research use only

Alternative Names

anti STAT3 antibody, anti APRF antibody, anti Signal transducer and activator of transcription 3 antibody, anti Signal transducer and activator of transcription 3 antibody, anti Acute-phase response factor antibody

Stat3 (C-term Tyr705) Antibody western blot analysis in A431 cell line lysates (35 ug/lane). This demonstrates the Stat3 (Tyr705) antibody detected the Stat3 (Tyr705) protein (arrow).

Quick Database Links

Gene Symbol

STAT3

UniProt

P40763

RefSeq (Protein):NP_003141.2, NP_644805.1, NP_998827.1