SOX2 Rabbit Polyclonal Antibody

SKU: orb1742373

Description

SOX2 antibody detects SOX2 protein, a basic helix-loop-helix transcription factor (predicted molecular weight of 34 kDa). SOX2 is an indispensable factor for regulating embryonic development and in the generation of inducible pluripotent stem (iPS) cells. It is also expressed in neural stem and progenitor cells. Dysregulation of SOX2 is associated with tumorigenesis.

Research Area

Stem Cell & Developmental Biology

Images & Validation

• Tested Applications: FC, ICC, IHC-Fr, IHC-P, IP, WB
• Dilution Range: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FCM: 1:50-1:200. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
• Reactivity: Frog, Human, Mouse, Rat, Rhinoceros
• Application Notes:
  Positive control: Mouse ESC , hESC , NT2D1 , NT2D1

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SOX2. The exact sequence is proprietary.
• Target: SRY-box 2
• Molecular Weight: 34
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS, 1% rAlbumin, 20% Glycerol, 0.025% ProClin 300.
• Concentration: 0.19 mg/ml (Please refer to the vial label for the specific concentration.)
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SRY-box 2 , ANOP3 , MCOPS3

Quick Database Links

Gene Symbol

SRY-box 2

UniProt

P48431