SOS2 (M) Antibody, Rabbit Polyclonal

SKU: orb67258

Description

Rabbit polyclonal to SOS2.Son of Sevenless (SOS) was discovered in Drosophila melanogaster. SOS has two humanhomologues, SOS1 and SOS2. SOS proteins are guanine-nucleotide releasing factor that canpromote the exchange of Ras-bound GDP by GTP to activate Ras in response to growth factorstimulation. SOS proteins also appear to serve as a guanine nucleotide exchanger for Rac and, thus,may be involved in cytoskeleton reorganization. SOS proteins may be recruited to different cellularlocations through interactions with the adaptor proteins Grb2 and E3b1.

Research Area

Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:2000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: middle region of human SOS2
• Molecular Weight: 153
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-SOS2 antibody,anti-Son of sevenless homolog 2 antibody,anti-SOS2 antibody

Western blot analysis of total cell extracts from human Hela using SOS2 antibody

Quick Database Links

UniProt

Q07890