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Catalog Number | orb67259 |
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Category | Antibodies |
Description | Rabbit polyclonal to SOS2.Son of Sevenless (SOS) was discovered in Drosophila melanogaster. SOS has two humanhomologues, SOS1 and SOS2. SOS proteins are guanine-nucleotide releasing factor that canpromote the exchange of Ras-bound GDP by GTP to activate Ras in response to growth factorstimulation. SOS proteins also appear to serve as a guanine nucleotide exchanger for Rac and, thus,may be involved in cytoskeleton reorganization. SOS proteins may be recruited to different cellularlocations through interactions with the adaptor proteins Grb2 and E3b1. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | C-terminal region of human SOS2 |
Dilution range | WB:1:500-1:2000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 153 |
UniProt ID | Q07890 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-SOS2 antibody,anti-Son of sevenless homolog 2 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela using SOS2 antibody