SNW1 Antibody / NCoA-62 / SKIP

• Catalog Number: orb1825525
• Category: Antibodies
• Description: Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: PCRP-SNW1-1C12
• Tested applications: FACS, IF
• Reactivity: Human
• Isotype: Mouse IgG2a
• Immunogen: A recombinant fragment of human SNW1 protein was used as the immunogen for the SNW1 antibody.
• Dilution range: Flow cytometry: 1-2ug/million cells,Immunofluorescence: 2-4ug/ml
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This SNW1 antibody is available for research use only.
• UniProt ID: Q13573
• Storage: Aliquot the SNW1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.