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Catalog Number | orb1823780 |
---|---|
Category | Antibodies |
Description | SmarcAL1 (SWI/SNF-related matrix-associated Actin-dependent regulator of chromatin subfamily A-like protein 1), also known as HARP (hepA-related protein) or HHARP, is a 954 amino acid member of the SWI/SNF family of helicase and ATPase proteins. Localized to the nucleus, SmarcAL1 is a ubiquitously expressed protein that functions in ATP-dependent nucleosomeremodeling activities. SmarcAL1 contains one conserved C-terminal SNF2 domain, one helicase ATP-binding domain and two HARP domains. Defects in the gene encoding SmarcAL1 are the cause of Schimke immuno-osseous dysplasia (SIOD), an autosomal recessive disorder characterized by renal dysfunction, spondyloepiphyseal dysplasia and T cell immunodeficiency. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | PCRP-SMARCAL1-1C4 |
Tested applications | IHC-P |
Reactivity | Human |
Isotype | Mouse IgG2c, kappa |
Immunogen | Recombinant full-length human SMARCAL1 protein was used as the immunogen for the SMARCAL1 antibody. |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
Conjugation | Unconjugated |
Formula | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
Hazard Information | This SMARCAL1 antibody is available for research use only. |
UniProt ID | Q9NZC9 |
Storage | Aliquot the SMARCAL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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