Smad5 Antibody

• Catalog Number: orb1731346
• Category: Antibodies
• Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. Smad5 is a receptor-regulated Smad (R-Smad). Smad5 is required for normal development of the cardiovascular system in vivo; lack of the Smad5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of Smad5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human SMAD5
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 52 kDa; Observed MW: 60 kDa
• Entrez: 4090
• UniProt ID: Q99717
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: DKFZp781C1895; DKFZp781O1323; Dwfc; hSmad 5; hSmad
• Note: For research use only
• Expiration Date: 12 months from date of receipt.