SMAC Antibody

• Catalog Number: orb1731348
• Category: Antibodies
• Description: Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, IHC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human Smac/Diablo
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 27 kDa; Observed MW: 21 kDa
• Entrez: 56616
• UniProt ID: Q9NR28
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: SMAC; DFNA64; DIABLO; SMAC3
• Note: For research use only
• Expiration Date: 12 months from date of receipt.