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Catalog Number | orb1732818 |
---|---|
Category | Antibodies |
Description | Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 1G7 |
Tested applications | ICC, WB |
Reactivity | Human, Mouse, Rat |
Isotype | Mouse IgG2b |
Immunogen | Purified recombinant human SirT2 protein expressed in E.coli. |
Concentration | 1mg/ml |
Dilution range | WB: 1/500-1/1000; ICC: 1/50-1/200 |
Conjugation | Unconjugated |
MW | Calculated MW: 43 kDa; Observed MW: 43 kDa |
Entrez | 22933 |
UniProt ID | Q8IXJ6 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3. |
Alternative names | SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacet Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Polyclonal | |
Unconjugated |
ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Polyclonal | |
Unconjugated |
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