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Catalog Number | orb1731357 |
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Category | Antibodies |
Description | Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle. |
Species/Host | Rabbit |
Clonality | Monoclonal |
Tested applications | IHC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | Recombinant protein of human SIRT2 |
Concentration | 1mg/ml |
Dilution range | IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100 |
Conjugation | Unconjugated |
MW | Calculated MW: 43 kDa; Observed MW: 39 kDa |
Entrez | 22933 |
UniProt ID | Q8IXJ6 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacet Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Polyclonal | |
Unconjugated |
ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Polyclonal | |
Unconjugated |
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