SIGIRR Rabbit Polyclonal Antibody

SKU: orb186004

Description

SIGIRR Rabbit Polyclonal Antibody

Research Area

Cell Biology, Interleukins, TLR Signaling Pathway

Images & Validation

• Tested Applications: ELISA, ICC, IF, IHC-Fr, IHC-P, WB
• Dilution range: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000
• Reactivity: Human
• Predicted Reactivity: Equine, Human, Mouse, Porcine, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human SIGIRR (121-220/410aa)
• Target: SIGIRR
• Molecular Weight: 46 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Disclaimer: For research use only

Alternative Names

Ig IL1 related receptor; MGC110992; SIGIR_HUMAN; SIGIRR; Single Ig IL 1 related receptor; Single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; Single Ig IL1R Related Molecule; Single immunoglobulin and toll interleukin 1 receptor(TIR) domain; Single immunoglobulin and toll interleukin 1 receptor domain; Single immunoglobulin domain containing IL1R related protein; Single immunoglobulin domain IL1R1 related; Single immunoglobulin domain-containing IL1R-related protein; TIR 8; TIR8; Toll/interleukin 1 receptor 8; Toll/interleukin-1 receptor 8.

Quick Database Links

Gene Symbol

SIGIRR

UniProt

Q6IA17

References

Yu Zhang 1, Beixi Shi 2, Yaxin Bi 3, Xiaxin Wu 2, Xiangning Li 2, Jinfeng Wu 2, Jiahui Qiu 2, Zhijie Lin 4, Guotao Lu 5, Weijuan Gong High-dose IL-37 promotes inflammatory activity of macrophage via Preferential ligation of the IL-18Rα Sci Rep, (2025)

PubMed: 40594247