SHMT1 Protein, Human, Recombinant (His)

Catalog Number: orb1961784

Catalog Number	orb1961784
Category	Small Molecules
Description	SHMT1 Protein, Human, Recombinant (His)
Purity	98.00%
MW	55 KDa, reducing conditions
Biological Activity	Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.
Note	For research use only
Expiration Date	12 months from date of receipt.

Recombinant Human SHMT1 Protein, His Tag [orb1551649]
Purity:
≥90% as determined by SDS-PAGE
Source:
This protein contains the human SHMT1(Met3-Phe483) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Sizes Available: 100 μg, 50 μg
Human SHMT1 protein (C-His) [orb312001]
Source:
Human Cells
Sizes Available: 50 μg, 1 mg, 500 μg, 10 μg

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human SHMT1(Met3-Phe483) was fused with the C-terminal His Tag and expressed in Mammalian cells.