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SHMT1 Protein, Human, Recombinant (His)
Catalog Number: orb1961784
| Catalog Number | orb1961784 |
|---|---|
| Category | Proteins |
| Description | Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome. |
| Tag | C-6xHis |
| Protein Sequence | Met3-Phe483 |
| UniProt ID | AAH07979.1 |
| MW | 55 KDa (reducing condition) |
| Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Expression System | HEK293 Cells |
| Biological Origin | Human |
| Expression Region | Met3-Phe483 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
Recombinant Human SHMT1 Protein, N-His-SUMO [orb2832814]
>90% as determined by SDS-PAGE.
62.89 kDa
100 μg, 20 μg, 50 μgRecombinant Human SHMT1 Protein, N-His-SUMO [orb2963950]
>90% as determined by SDS-PAGE.
62.89 kDa
1 mg, 100 μg, 50 μg
