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| Catalog Number | orb36781 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal antibody to SFRS5 in that SR proteins own a characteristic C-terminal Ser/Arg-rich repeat (RS domain) of variable length and constitute a family of highly conserved nuclear phosphoproteins that can function as both essential and alternative pre-mRNA splicing factors. The binding of SR proteins to pre-mRNA appears to be one of the earliest steps in spliceosome assembly, enhancing the binding of U1 snRNP to the 5' splice site to form a commitment complex. |
| Target | SRSF5 |
| Clonality | Polyclonal |
| Species/Host | Rabbit |
| Isotype | Rabbit IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat |
| Form/Appearance | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Immunogen | Synthetic Peptide |
| UniProt ID | Q13243 |
| MW | 31264 |
| Tested applications | FC, WB |
| Dilution range | WB: 1:1000, FACS: 1:10-50 |
| Antibody Type | Primary Antibody |
| Clone Number | RB19850 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles |
| Alternative names | Anti-Splicing factor antibody, anti-arginine/serin Read more... |
| Research Area | Molecular Biology |
| Note | For research use only |
| NCBI | NP_008856.2, NP_001034554.1 |

Western blot analysis of SFRS5 antibody (Center Y85) in NCI-H460 cell line lysates (35 ug/lane). SFRS5 (arrow) was detected using the purified Pab.

SFRS5 Antibody (Center Y85) flow cytometric analysis of NCI-H292 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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